Active substance (s): 550 mg naproxen
Market Forms: 10 tablets, 20 tablets in blisters.
Usage: daily dose of 550 mg initially, then 275 mg every 6-8 hours. Maximum daily dose of 1375 mg.
Indications in neurology: migraine prophylaxis and treatment of acute migraine, neuralgia, siyatalji, myalgia. to ensure in gynecology: dysmenorrhea and intrauterine device use, the uterine relaxation and analgesia. In dentistry painful dental problems, tooth extractions and anti-inflammatory analgesics in pain after the common. In surgery and traumatology of the musculoskeletal system: sprains, stress and post-operative pain, such as in sports accidents. Musculoskeletal system: bursitis, tendinitis, synovitis, tenosynovitis, lumbago. Infectious diseases: in addition to specific treatment and anti-inflammatory analgesic and antipyretic purposes. Rheumatic diseases: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout treatment is indicated.
Contraindications: In people sensitive to drugs such as naproxen and aspirin, etc.. Medications for asthma, allergic rhinitis and urticaria show a cross between this group of drugs can cause an allergic reaction (anaphylactic reaction to create risk), should not in patients with active gastric or duodenal ulcers may be used.
Notes: 16 years shall not be given to small children and nursing mothers. Should not be used during pregnancy if it is required. The first and third trimesters of pregnancy, especially the use and bring benefits to the patient a better assessment of risks must be made. Can the elimination of the drug in the elderly should be careful, the lowest effective dose should be used. Heart failure and dysfunction, renal and liver function should be used with caution in patients with diseases.
Side effects: abdominal pain, nausea, mild peripheral edema, tinnitus, dizziness and slight side effects may occur rarely. Very rarely, hair loss, hematuria, gastrointestinal bleeding and / or perforation, have been reported, including granulocytopenia agranülositozis, allergic skin rashes.
Drug Interactions: hydantoin, sulfonamide or strongly bound to proteins, such as sulfonylurea drugs in people with naproxen, the drug cut off their ties and the protein itself is able to use their influence by moving to increase the dosage should be adjusted. Similarly, the field of oral anticoagulant therapy should be considered. In combination with probenecid significantly increased half-life of naproxen. Will reduce tubular secretion may increase methotrexate toxicity. Should be used with caution. Propranolol and other beta-blockers the blood pressure lowering effect. be Natriuretic effect of furosemide, some non-steroidal anti-inflammatory drugs have been reported to be inhibited. The use of naproxen should be given between 48 hours before adrenal function tests. Combine the results of the 17-ketosteroid test and urine tests may also affect 5 HIAA.
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